Physiology

Jitendra Behari's Biophysical Bone Behaviour: Principles and Applications PDF

By Jitendra Behari

ISBN-10: 047082400X

ISBN-13: 9780470824009

Biophysical Bone Behaviour: rules and purposes is the end result of efforts to narrate the biophysical phenomena in bone to bone progress and electric habit. Behari develops a bridge among physics and biology of bone resulting in its medical purposes, essentially electro stimulations in fracture therapeutic and osteoporosis. The publication relies upon authors personal examine paintings and his evaluation articles within the region, and up-to-date with the newest examine effects. the 1st publication devoted to biophysical bone behaviorDevelops the connection among the biophysics and biology of bone into an crucial unitSpans easy biophysical reports and medical applicationsLinks some of the issues jointly to provide readers a holistic realizing of the areaPresents all significant learn findings approximately bone and biophysics Readers can entry the whole checklist of references on the better half site: www.wiley.com/go/behari

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Additional resources for Biophysical Bone Behaviour: Principles and Applications

Example text

The ionized calcium is diffusible, the citrate calcium is not ionized but is also diffusible, while the calcium proteinate is neither ionized nor diffusible. The distribution of calcium (Lingarde, 1972; Walser, 1961) and its fall is affected by age. e. [H þ ] ion concetration) level is a controlling parameter which affects Ca2þ . Increased protein calcium binding counteracts Ca2þ homeostatic control mechanism as the Ca2þ decreases. The amount of diffusible non-ionized calcium is small and is generally believed to be of little clinical interest except in patients (Lingarde, 1973).

Their presence, which accounts for about 65 wt% of bone, provides most of the stiffness and strength of bone (Glimcher, 1992). , 1997). Correlative to the increase in the diameter of the middiaphyses of long bone, occurring principally by periosteal bone Elements of Bone Biophysics 13 deposition and the later resorption (Enlow, 1991), endosteal bone becomes more mineralized than the former. , 1997). Lees and Davidson (1977,1979) suggested that mineralization causes additional crosslinkages to be set up, some between TC units but more between the mineral, whether crystalline or amorphous, and the TC units.

The spin–spin relaxation time (T2, for 2H2O on collagen) also decreases with decreasing water content. The relaxation times are strongly frequency dependent. The loosely associated water is what is referred to as “bulk water” (free water) that fills the pores of the calcified matrix making up the Haversian and lacuno-canalicular system. It is this fraction of water that has been shown to confer the unique viscoelastic properties of bone, which are largely lost after drying. , 2000). Notably, the binding state of pore water depends on its proximity to the surface and thus is expected to be greatest in the canaliculi measuring less than 1 mm in diameter.

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Biophysical Bone Behaviour: Principles and Applications by Jitendra Behari


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