Cardiovascular

New PDF release: Cardiovascular and Musculoskeletal Systems

By John F. Van Vleet, Victor J. Ferrans (auth.), Thomas Carlyle Jones D.V.M., D.Sc., Ulrich Mohr M.D., Ronald Duncan Hunt D.V.M. (eds.)

ISBN-10: 3642765335

ISBN-13: 9783642765339

ISBN-10: 3642765351

ISBN-13: 9783642765353

This quantity is one in every of a collection of concise, good illustrated and authoritative reports of usual and experimental lesions of laboratory animals (rat, mouse and hamster) prepared by means of organ platforms. designated differential diagnostic standards and terminology are given emphasis. integrated are important facts on pathogenesis, etiology, biologic habit, frequency in several traces and lower than various laboratory stipulations.

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Initial cardiac lesions are (Fig. 14) and, in severely calcified myocytes, cel- prominent by 30-50 days of age as focal lular details are completely obscured by irregu- myolysis and focal necrosis with myocyte calcifilar calcium salt granules (Figs. 15, 16). With the cation (Van Fleet and Ferrans 1986). Spontaexception of cardiomyopathic BIO hamster neous non-age-related myocardial calcifications, strains, usually neither interstitial calcification which remain clinically inapparent, were also nor inflammatory or fibrous reactions can be ob- observed in a 100% incidence of male and feserved.

1983), but vascuUltrastructure lar calcification of coronary vessels can also Electron microscopic features of myocardial cal- occur independently of myocardial calcification cification have been described by Burbach (Doi et al. 1987). 6 cardiomyopathic hamsters. quently observed in a generalized form, involvCalcium deposition was observed in mitochron- ing not only myocardium or cardiac arteries, dira after myocyte breakdown and disruption of but also aorta, renal, and gastric arteries, the sarcolemma as well as in interstitial areas.

1983) to 31 % in females and 48% in males of the Unei: cases of severe calcification (Fig. 16). (SYR) stock (Birt et al. 1985). Affected hamsters often have accompanying mineralization of cardiac arteries (Schmidt et al. 1983), but vascuUltrastructure lar calcification of coronary vessels can also Electron microscopic features of myocardial cal- occur independently of myocardial calcification cification have been described by Burbach (Doi et al. 1987). 6 cardiomyopathic hamsters. quently observed in a generalized form, involvCalcium deposition was observed in mitochron- ing not only myocardium or cardiac arteries, dira after myocyte breakdown and disruption of but also aorta, renal, and gastric arteries, the sarcolemma as well as in interstitial areas.

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Cardiovascular and Musculoskeletal Systems by John F. Van Vleet, Victor J. Ferrans (auth.), Thomas Carlyle Jones D.V.M., D.Sc., Ulrich Mohr M.D., Ronald Duncan Hunt D.V.M. (eds.)


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