Physiology

New PDF release: Ciba Foundation Symposium 155 - Myopia and the Control of

By CIBA Foundation Symposium

ISBN-10: 0470514027

ISBN-13: 9780470514023

ISBN-10: 0471926922

ISBN-13: 9780471926924

Myopia, the commonest affliction of the attention, impacts eighty% of the inhabitants of a few international locations. even supposing its foundation continues to be doubtful, fresh improvement of animal types have accredited checks of speculation as to myopia's origins. The symposium lawsuits disguise general progress of the attention together with the jobs of peptide components, metabolism and accomodation, research of the deficiencies that bring about myopia and different refractive problems.

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Extra info for Ciba Foundation Symposium 155 - Myopia and the Control of Eye Growth

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If they are not identical, genetic differences, even between monkeys of the same species, might influence your results. Raviola: Our accuracy, at best, is of the order of the diopter and we prefer to rely on axial length measurements to assess interocular differences. The 42 Discussion issue of the genetic determinants of refraction is discussed in our paper (P 35). Goldschmidt: Many children treated with atropine retain a residual degree of accommodation. Raviola: It seems to be more difficult to paralyse accommodation in the rhesus macaque than in the stumptailed macaque.

Dashed line: open eye. Because retinal ganglion cells degenerate when their axons are severed, we wanted to be sure that the retina was largely intact in the animal shown in Fig. 10 that was reared in the dark for two years after optic nerve section. Light microscopy showed that fewer and smaller cell bodies were present in the ganglion cell layer. These cell bodies probably belonged to displaced amacrine cells. The inner plexiform layer was present and exhibited, at the electron microscopic level, its usual complement of ribbon and conventional synapses.

As the number of animals we have raised in the dark has increased, we are no longer convinced that our interpretation is correct. The eyes, open or closed, of the dark-reared rhesus macaques (Figs. 5 and 10) exhibit a wide variation in vitreous length and refraction; a similar, less dramatic variation is observed in the eyes of newborn animals (Fig. 11). If one considers dark rearing as an experimental continuation of the prenatal condition, one may regard the geometry and refraction of the darkreared eye as outcomes of a purely genetic process not involving the interplay of environmental influences.

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