By Macdonald Dick
This quantity specializes in the sensible facets of scientific electrophysiology of cardiac arrhythmias within the younger as practiced within the division of Pediatric Cardiology on the college of Michigan. Cardiac arrhythmias in little ones are usually symptomatic in addition to scary to the kid sufferer and mother or father. This quantity is meant as a realistic advisor for the beginner or professional general practitioner provided with a toddler with a cardiac arrhythmia.
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Additional info for Clinical Cardiac Electrophysiology in the Young (Developments in Cardiovascular Medicine)
The membrane potential therefore moves towards the equilibrium potential of sodium (∼+40 mV). The stimulus that generates the action potential elicits an all or nothing response. If the stimulus is sub threshold, the membrane is transiently depolarized and then quickly returns to the resting potential. If the stimulus is of sufﬁcient intensity to raise the membrane potential above the threshold level, a maximal response is elicited and an action potential is generated. , a stimulus of greater intensity does not result in an increase in Vmax ).
IK1 . IK1 is the dominant resting conductance in the heart, setting the resting membrane potential in atrial, ventricular, and Purkinje cells. The heterogeneous density of channel distribution is greater in the ventricles relative to the atrium, but relatively sparse in nodal cells. IK1 has been demonstrated to inactivate at sustained depolarized potentials, 23 such as during the plateau phase of the action potential. IK-Ach . Acetylcholine, which is released from the cardiac parasympathetic nerves, acts on type 2 muscarinic receptors to open the channels via a G-protein dependent mechanism.
Electrical heterogeneity within the ventricular wall. Basic Res Cardiol 2001;96:517–527. 3 Clinical Electrophysiology of the Cardiac Conduction System Macdonald Dick II, Peter S. Fischbach, Ian H. Law, and William A. Scott Recording the human cardiac biological signal from the body surface, the electrocardiogram (ECG) has been used for at least seven decades in the diagnosis and management of cardiac disorders in infants and children, primarily by examining for criteria of hypertrophy or dilatation imposed by congenital cardiac malformations, rheumatic heart disease or other acquired heart conditions.
Clinical Cardiac Electrophysiology in the Young (Developments in Cardiovascular Medicine) by Macdonald Dick