By Chourmouzios Arampatzis, Eugene P McFadden, Lampros K Michalis, Renu Virmani, Patrick W. Serruys
Coronary Atherosclerosis: present administration and therapy addresses the major explanation for loss of life around the world - coronary artery disorder. Atherosclerosis has a extensive diversity of disorder manifestations looking on the measure of the stenosis, and the sensible prestige of the coronary plaque and is a ailment cardiologists deal with on a daily basis. occurrence of coronary artery affliction is expanding as a better variety of humans live longer and emerging premiums of weight problems give a contribution to negative health.This fresh name, written through a number one foreign workforce of Editors, addresses the pathophysiology of illness, esta Read more...
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Extra resources for Coronary atherosclerosis: current management and treatment
Abbreviations: CV, cardiovascular; DBP, diastolic blood pressure; HT, hypertension; MS, metabolic syndrome; OD, organ damage; SBP, systolic blood pressure. 14 screening and identifying high-risk individuals in fatty streaks is derived from LDL-cholesterol. The second stage consists of the formation of fibrous plaques in which a layer of scar tissue overlies a lipid-rich core. Other risk factors contribute to plaque growth in this phase. The third stage is represented by the development of unstable plaques that are prone to rupture and formation of luminal thrombosis.
Primary prevention of coronary heart disease: integrating risk assessment with intervention. Circulation 1999; 100: 988–98. 3. Sacks FM, Pfeffer MA, Moye LA, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators. N Engl J Med 1996; 335: 1001–9. 4. The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group. Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels.
The importance of stratifying patients relies on the fact that the benefit of CVD prevention strategies depends on the underlying level of CV risk. It is important to estimate the absolute reduction in risk to adequately assess the risk versus benefit of any prevention strategy. For a similar relative risk reduction across risk strata, the absolute reduction is indeed greater in a higher risk cohort than in a lower risk cohort. Two different but complementary approaches are used for the prevention of CVD.
Coronary atherosclerosis: current management and treatment by Chourmouzios Arampatzis, Eugene P McFadden, Lampros K Michalis, Renu Virmani, Patrick W. Serruys