Physiology

Download e-book for kindle: Corticonics: Neural Circuits of the Cerebral Cortex by M. Abeles

By M. Abeles

ISBN-10: 0521376173

ISBN-13: 9780521376174

This publication fulfills that desire by way of combining reports of anatomy and body structure and mathematical and desktop modeling to acquire a quantitative description of cortical services. the cloth is gifted didactically; it begins with descriptive anatomy and comprehensively examines all features of modeling. The booklet progressively leads the reader from a macroscopic view of cortical anatomy and an outline of normal electrophysiological homes of unmarried neurons to neural community types and synchronous firing chains of neurons. alongside the best way, the main smooth traits of neural community modeling are explored

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Extra info for Corticonics: Neural Circuits of the Cerebral Cortex

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7. Anterograde staining. Some materials are taken up by the cell body and then transmitted down the axon all the way to its terminals. Thus, one can inject material into a region, wait until it is transported to the terminals, and then discover the locations of these terminals. In the past, the materials most frequently employed for anterograde staining were radioactive amino acids. These are actively transported into the neuron and incorporated into proteins, some of which are transported down the axon.

In 1861, Broca found that damage to a small localized region in the brain of a patient resulted in disruption of the motor aspects of speech. In 1870, Hitzig showed that electrical stimulation of certain cortical regions could induce movements. Finally, Jean Bouillaud (1796-1881) produced maps showing the motor, somatosensory, visual, and auditory regions of the cortex. Bouillaud suggested that for every sensory (and motor) system there was a primary cortical area surrounded by a secondary sensory area and that in between them there were association areas.

The idea that functions can be distributed across wide cortical areas has prompted many studies using statistical tools to evaluate cortical function and connectivity. The reader can gain much insight into the current debates by studying the behavioral work of Lashley, the anatomical work of Sholl [1956], the electrophysiological work of Burns [1958, 1968], and the multidisiplinary work of John [1967]. The notion that cortical functions were carried out through interactions among widespread areas was not accepted universally.

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Corticonics: Neural Circuits of the Cerebral Cortex by M. Abeles


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